I-KaiBiLi^TMI-COVID-19 Neutralization Antibody Rapid Test Device iyi-lateral flow chromatographic immunoassay yokutholwa kwekhwalithi ye-neutralization antibody kuya ku-2019-Novel Coronavirus egazini lomuntu lonke, i-serum noma isampula se-plasma.Isetshenziswa kuphela njengenkomba eyisithenjwa yomphumela womgomo.Ayilungele ukuhlolwa kwabantu okuvamile.Ama-coronavirus anoveli awohlobo lwe-β.

I-COVID-19 yisifo esithathelwanayo sokuphefumula esinamandla.I-2019-nCOV inamaprotheni esakhiwo amaningana afaka i-spike (S), imvilophu (E), ulwelwesi (M) kanye ne-nucleocapsid (N).Iphrotheni ye-spike (S) iqukethe isizinda esibopha i-receptor (RBD), esibophezelekile ukuqaphela i-cell surface receptor, i-angiotensin converting enzyme-2 (ACE2).Kutholwe ukuthi i-RBD ye-2019-nCOV S protein isebenzisana ngokuqinile nesamukeli somuntu se-ACE2 okuholela ku-endocytosis kumaseli abamba amaphaphu ajulile kanye nokuphindaphindeka kwegciwane.Ukutheleleka nge-2019-nCOV kuqala impendulo yokuzivikela komzimba, okubandakanya ukukhiqizwa kwamasosha omzimba egazini.Amasosha omzimba afihliwe ahlinzeka ngokuvikeleka ezifweni zesikhathi esizayo ezivela kumagciwane, ngoba ahlala ohlelweni lokujikeleza kwegazi izinyanga kuya eminyakeni ngemva kokutheleleka futhi azobopha ngokushesha futhi ngokuqinile ku-pathogen ukuze avimbe ukungena kwamangqamuzana nokuphindaphinda.Lawa ma-antibodies abizwa ngokuthi ama-neutralization antibodies.